Across TCGA patient cohorts, HCAR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,376 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HCAR1-associated proteins across cancer lineages are SLC9A3R2, LRATD2, and CAB39L. Each is linked with HCAR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HCAR1-to-partner and partner-to-HCAR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR1→partner) and Y-score (partner→HCAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC9A3R2 →	+0.568	+1.350	.001	.001	3	4
BRCA	LRATD2 →	+0.670	+1.719	<.001	<.001	3	4
BRCA	CAB39L →	+0.588	+1.630	<.001	<.001	3	3
BRCA	CHCHD10 →	-0.503	-1.492	<.001	<.001	3	3
BRCA	CRIP2 →	+0.548	+1.096	<.001	<.001	3	3
OV	ATP8B1 →	+0.626	+1.236	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,376 associations by consensus.

Exploration

HCAR1 survival (RNA) · tumor vs normal (RNA) · all HCAR1 data types