Across TCGA patient cohorts, HCAR1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HCAR1-associated genes across cancer lineages are Platelets, MEP, and pDC. Each is linked with HCAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCAR1-to-partner and partner-to-HCAR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR1→partner) and Y-score (partner→HCAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Platelets →	+0.019	+2.447	.022	.030	3	2
UCEC	MEP →	+0.030	+1.885	.020	.032	3	1
UCEC	pDC →	+0.051	+3.008	.024	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

HCAR1 survival (RNA) · tumor vs normal (RNA) · all HCAR1 data types