Across TCGA cell cohorts, HCAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,642 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HCAR1-associated GO terms across cancer lineages are Positive regulation of intracellular transport, Negative regulation of myoblast fusion, and Microglia development. Each is linked with HCAR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HCAR1-to-partner and partner-to-HCAR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR1→partner) and Y-score (partner→HCAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of intracellular transport →	+0.053	+1.860	.008	.005	3	8
SKIN	Negative regulation of myoblast fusion →	+0.064	+0.292	<.001	.001	3	8
OVARY	Microglia development →	-0.219	-0.893	<.001	<.001	3	8
OESOPHAGUS	Negative regulation of actin filament polymerization →	+0.106	+0.987	.001	.004	3	7
SOFT_TISSUE	Regulation of intracellular transport →	+0.049	+0.299	<.001	.008	3	7
STOMACH	Regulation of cellular component size →	+0.055	+1.666	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,642 associations by consensus.

Exploration

HCAR1 survival (RNA) · tumor vs normal (RNA) · all HCAR1 data types