HBS1L

Across TCGA patient cohorts, HBS1L protein abundance is significantly associated with the protein abundance of many other proteins, with 12,407 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HBS1L-associated proteins across cancer lineages are RNGTT, TCP1, and PELO. Each is linked with HBS1L in more than 7 cancer types. Because this analysis shows association rather than direction, both HBS1L-to-partner and partner-to-HBS1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBS1L versus RNGTT in COAD, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HBS1L→partner) and Y-score (partner→HBS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNGTT →	+0.514	+0.285	<.001	<.001	3	8
HNSC	TCP1 →	+0.271	+0.194	<.001	<.001	3	8
GBM	PELO →	+0.278	+0.310	<.001	<.001	3	8
HNSC	CCT4 →	+0.242	+0.185	<.001	<.001	3	7
LUAD	CCT5 →	+0.220	+0.199	<.001	<.001	3	7
HNSC	CCT6A →	+0.414	+0.189	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,407 associations by consensus.

HBS1L vs RNGTT — COAD

Explore this scatter interactively →