HBS1L

Across TCGA cell cohorts, HBS1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,653 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HBS1L-associated GO terms across cancer lineages are Regulation of metaphase/anaphase transition of cell cycle, Positive regulation of chromosome condensation, and Regulation of mitotic metaphase/anaphase transition. Each is linked with HBS1L in more than 16 cancer types. Because this analysis shows association rather than direction, both HBS1L-to-partner and partner-to-HBS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metaphase/anaphase transition of cell cycle grouped by HBS1L-low versus HBS1L-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HBS1L→partner) and Y-score (partner→HBS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.128	+1.124	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of chromosome condensation →	+0.264	+1.042	<.001	<.001	3	17
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.142	+1.124	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.127	+1.205	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Protein localization to kinetochore →	+0.167	+1.527	.002	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome segregation →	+0.126	+1.027	.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Regulation of metaphase/anaphase transition of cell cycle by HBS1L expression — KIDNEY

Explore this box plot interactively →