HBQ1

Across TCGA cell cohorts, HBQ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,024 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HBQ1-associated GO terms across cancer lineages are Positive regulation of response to type II interferon, Positive regulation of type II interferon-mediated signaling pathway, and Regulation of sodium ion transmembrane transport. Each is linked with HBQ1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HBQ1-to-partner and partner-to-HBQ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of response to type II interferon grouped by HBQ1-low versus HBQ1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HBQ1→partner) and Y-score (partner→HBQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of response to type II interferon →	-1.333	-1.654	<.001	<.001	3	10
BONE	Positive regulation of type II interferon-mediated signaling pathway →	-1.333	-1.654	<.001	<.001	3	10
BONE	Regulation of sodium ion transmembrane transport →	-0.168	-1.411	<.001	<.001	3	9
CNS	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.073	+0.803	<.001	<.001	3	9
OVARY	Renal vesicle formation →	+1.064	+1.530	<.001	.001	3	8
OVARY	Metanephric renal vesicle formation →	+1.064	+1.530	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,024 associations by consensus.

Positive regulation of response to type II interferon by HBQ1 expression — BONE

Explore this box plot interactively →