HBP1

Across TCGA patient cohorts, HBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,085 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HBP1-associated proteins across cancer lineages are ZKSCAN1, EVI2B, and GATAD2B. Each is linked with HBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HBP1-to-partner and partner-to-HBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBP1 versus ZKSCAN1 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HBP1→partner) and Y-score (partner→HBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZKSCAN1 →	+0.371	+0.423	<.001	.001	3	5
BRCA	EVI2B →	-0.757	-0.560	<.001	.001	3	5
HNSC	GATAD2B →	+0.256	+0.456	.001	<.001	3	5
HNSC	SRP72 →	-0.206	-0.483	<.001	<.001	3	5
GBM	RO60 →	+0.234	+0.343	<.001	.001	3	5
HNSC	MEPCE →	+0.279	+0.391	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,085 associations by consensus.

HBP1 vs ZKSCAN1 — HNSC

Explore this scatter interactively →