HBP1

Across TCGA patient cohorts, HBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,428 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HBP1-associated genes across cancer lineages are GHDC, CIRBP, and ADAMTS9-AS2. Each is linked with HBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HBP1-to-partner and partner-to-HBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBP1 versus GHDC in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBP1→partner) and Y-score (partner→HBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GHDC →	+0.821	+0.396	<.001	<.001	3	5
OV	CIRBP →	+0.863	+0.532	<.001	<.001	3	5
UCEC	ADAMTS9-AS2 →	+1.400	+0.393	<.001	<.001	3	5
LUAD	PRX →	+0.572	+0.313	<.001	.001	3	4
OV	PEX12 →	+0.522	+0.323	<.001	.006	3	4
OV	HDAC5 →	+0.690	+0.414	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,428 associations by consensus.

HBP1 vs GHDC — OV

Explore this scatter interactively →