HBP1

Across TCGA cell cohorts, HBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,605 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HBP1-associated GO terms across cancer lineages are Macroautophagy, Autophagosome assembly, and Process utilizing autophagic mechanism. Each is linked with HBP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both HBP1-to-partner and partner-to-HBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by HBP1-low versus HBP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HBP1→partner) and Y-score (partner→HBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Macroautophagy →	+0.101	+1.371	<.001	<.001	3	17
BLOOD_Myeloma	Autophagosome assembly →	+0.080	+1.127	<.001	.004	2	18
STOMACH	Process utilizing autophagic mechanism →	+0.103	+1.312	<.001	<.001	3	17
STOMACH	Autophagy →	+0.103	+1.312	<.001	<.001	3	17
STOMACH	Vesicle budding from membrane →	+0.098	+1.085	<.001	.001	3	16
BLOOD_Myeloma	Autophagosome organization →	+0.069	+1.056	.001	.009	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,605 associations by consensus.

Macroautophagy by HBP1 expression — STOMACH

Explore this box plot interactively →