Across TCGA patient cohorts, HBE1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,977 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HBE1-associated genes across cancer lineages are HEMGN, HBA2, and HBA1. Each is linked with HBE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HBE1-to-partner and partner-to-HBE1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBE1→partner) and Y-score (partner→HBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HEMGN →	+0.555	+1.449	<.001	<.001	3	3
LSCC	HBA2 →	+2.247	+0.958	<.001	<.001	3	3
LSCC	HBA1 →	+1.410	+0.986	<.001	<.001	3	3
OV	ACTG1P14 →	+0.794	+1.346	.002	.003	3	3
LSCC	HBB →	+2.321	+0.992	<.001	<.001	3	3
CCRCC	SLC4A1 →	+0.695	+1.526	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,977 associations by consensus.

Exploration

HBE1 survival (RNA) · tumor vs normal (RNA) · all HBE1 data types