Across TCGA patient cohorts, HBA2 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HBA2-associated genes across cancer lineages are RNU6-793P, MIR1263, and MIR1283-1. Each is linked with HBA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HBA2-to-partner and partner-to-HBA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA2→partner) and Y-score (partner→HBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-793P →	+0.329	+7.741	<.001	.009	3	1
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	1
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	1
COAD	MTATP6P30 →	+0.147	+7.741	<.001	.009	3	1
HNSC	RPL23AP39 →	+0.087	+5.241	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

HBA2 survival (RNA) · tumor vs normal (RNA) · all HBA2 data types