Across TCGA patient cohorts, HBA1 RNA expression is significantly associated with the RNA expression of many other genes, with 13,613 significant associations in total. READ shows the largest number of these associations.

The most reproducible HBA1-associated genes across cancer lineages are HBB, HBA2, and HBM. Each is linked with HBA1 in more than 33 cancer types. Because this analysis shows association rather than direction, both HBA1-to-partner and partner-to-HBA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA1→partner) and Y-score (partner→HBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	HBB →	+4.254	+3.578	<.001	<.001	3	34
LAML	HBA2 →	+4.206	+3.595	<.001	<.001	3	34
LAML	HBM →	+2.986	+3.348	<.001	<.001	3	27
LAML	ALAS2 →	+3.645	+3.505	<.001	<.001	3	27
LAML	PF4 →	+1.823	+1.869	<.001	<.001	2	22
MESO	CLDN5 →	+1.398	+1.002	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,613 associations by consensus.

Exploration

HBA1 survival (RNA) · tumor vs normal (RNA) · all HBA1 data types