Across TCGA patient cohorts, HBA1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible HBA1-associated genes across cancer lineages are TTTY11, DAZ3, and SNORD115-21. Each is linked with HBA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HBA1-to-partner and partner-to-HBA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA1→partner) and Y-score (partner→HBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TTTY11 →	+0.054	+7.640	<.001	.009	3	1
BLCA	DAZ3 →	+0.024	+7.640	<.001	.009	3	1
BLCA	SNORD115-21 →	+0.442	+7.640	<.001	.009	3	1
BLCA	RNA5SP22 →	+0.218	+7.640	<.001	.009	3	1
COAD	RNU6-1113P →	+0.339	+7.741	<.001	.009	3	1
BLCA	RNU7-138P →	+0.527	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

HBA1 survival (RNA) · tumor vs normal (RNA) · all HBA1 data types