Across TCGA cell cohorts, HBA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,617 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HBA1-associated GO terms across cancer lineages are Carbon dioxide transport, Response to interleukin-9, and Regulation of calcium ion transport into cytosol. Each is linked with HBA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HBA1-to-partner and partner-to-HBA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA1→partner) and Y-score (partner→HBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Carbon dioxide transport →	+2.144	+3.147	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Response to interleukin-9 →	-0.199	-1.044	.001	.002	3	6
BREAST	Regulation of calcium ion transport into cytosol →	-0.171	-1.361	.004	.006	2	7
BREAST	Aerobic electron transport chain →	+0.074	+0.860	<.001	.005	3	6
BREAST	ATP synthesis coupled electron transport →	+0.071	+0.894	<.001	.004	3	6
BREAST	Mitochondrial ATP synthesis coupled electron transport →	+0.071	+0.894	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

Exploration

HBA1 survival (RNA) · tumor vs normal (RNA) · all HBA1 data types