Across TCGA cell cohorts, HBA1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,328 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HBA1-associated genes across cancer lineages are ACSM3, FN3KRP, and MCIDAS. Each is linked with HBA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HBA1-to-partner and partner-to-HBA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA1→partner) and Y-score (partner→HBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ACSM3 →	-2.631	-2.080	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	FN3KRP →	-1.332	-1.638	<.001	.003	3	4
UPPER_AERODIGESTIVE_TRACT	MCIDAS →	-0.808	-2.133	<.001	.001	3	4
UPPER_AERODIGESTIVE_TRACT	CFAP20 →	-0.610	-1.147	.007	.009	3	4
LUNG_SCLC	TM9SF1 →	+0.803	+2.422	.002	.009	3	4
KIDNEY	NCEH1 →	-1.947	-2.477	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,328 associations by consensus.

Exploration

HBA1 survival (RNA) · tumor vs normal (RNA) · all HBA1 data types