HAVCR2

Across TCGA patient cohorts, HAVCR2 mutation is significantly associated with the RNA expression of many other genes, with 2,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAVCR2-associated genes across cancer lineages are LINC01491, TUBBP3, and LINC01607. Each is linked with HAVCR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HAVCR2-to-partner and partner-to-HAVCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01491 grouped by HAVCR2-low versus HAVCR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAVCR2→partner) and Y-score (partner→HAVCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01491 →	+0.203	+3.225	<.001	<.001	3	3
CESC	TUBBP3 →	+0.083	+5.539	<.001	.004	3	2
UCEC	LINC01607 →	-0.840	-4.148	<.001	<.001	3	2
UCEC	GGA1 →	+0.267	+2.716	.008	.003	3	2
UCEC	RHBDD3 →	+0.437	+2.906	.001	.001	3	2
UCEC	CYP27C1 →	-0.330	-3.000	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,176 associations by consensus.

LINC01491 by HAVCR2 expression — SKCM

Explore this box plot interactively →