HAVCR2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HAVCR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,946 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAVCR2-associated GO terms across cancer lineages are Regulation of myeloid dendritic cell activation, Regulation of myoblast fusion, and Vesicle budding from membrane. Each is linked with HAVCR2 in more than 15 cancer types. Because this analysis shows association rather than direction, both HAVCR2-to-partner and partner-to-HAVCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myeloid dendritic cell activation grouped by HAVCR2-low versus HAVCR2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAVCR2→partner) and Y-score (partner→HAVCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRegulation of myeloid dendritic cell activation →+1.229+2.557<.001<.001316
CNSRegulation of myoblast fusion →+0.036+0.260.008.00538
LARGE_INTESTINEVesicle budding from membrane →+0.064+0.195<.001.00236
KIDNEYRegulation of organelle assembly →+0.034+0.438.004.00536
CNSRegulation of macroautophagy →+0.040+0.349<.001.00736
CNSNegative regulation of myoblast fusion →+0.045+0.281.002.00236
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,946 associations by consensus.

Regulation of myeloid dendritic cell activation by HAVCR2 expression — BLOOD_Lymphoma

Box plot of Regulation of myeloid dendritic cell activation in HAVCR2-low vs HAVCR2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration