HAVCR1

Across TCGA cell cohorts, HAVCR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,540 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HAVCR1-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Positive regulation of amino acid metabolic process. Each is linked with HAVCR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HAVCR1-to-partner and partner-to-HAVCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by HAVCR1-low versus HAVCR1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAVCR1→partner) and Y-score (partner→HAVCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.047	+0.080	<.001	.001	3	6
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.146	+0.093	.001	.001	2	6
KIDNEY	Positive regulation of amino acid metabolic process →	-0.275	-3.269	.001	.008	3	5
OVARY	Regulation of kidney size →	+1.558	+2.983	<.001	<.001	3	5
SKIN	Cortical actin cytoskeleton organization →	+0.068	+0.095	.004	.005	3	5
LIVER	Negative regulation of cartilage development →	-0.191	-3.421	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,540 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by HAVCR1 expression — SKIN

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