HAUS8

Across TCGA pan-cancer cohorts, HAUS8 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HAUS8 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher HAUS8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated HAUS8 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

DLBC, SKCM, and UCEC are the cancer types where HAUS8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	All	0.054	0.842	<.001	12	view →
SKCM	DFS	Median	III,IV	0.063	0.648	.003	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
BLCA	OS	Median	II,III,IV	1.000	0.408	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HAUS8–DLBC (OS)

Open the DLBC breakdown →