HAUS7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, HAUS7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HAUS7 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher HAUS7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated HAUS7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where HAUS7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileAll0.6160.885.00719view →
LSCCOSMedianAll0.9040.685.0048view →
LUADDFSQuartileII,III,IV0.7270.407.0294view →
HNSCOSMedianAll0.8010.909.0174view →
UCECDFSMedianAll0.9351.000.0204view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration