HAUS6

Across TCGA patient cohorts, HAUS6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,817 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HAUS6-associated genes across cancer lineages are POLE2, MCM4, and DCLRE1B. Each is linked with HAUS6 in more than 6 cancer types. Because this analysis shows association rather than direction, both HAUS6-to-partner and partner-to-HAUS6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAUS6 versus POLE2 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS6→partner) and Y-score (partner→HAUS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	POLE2 →	+0.970	+0.523	.004	.003	3	6
OV	MCM4 →	+1.289	+0.600	<.001	.003	3	6
OV	DCLRE1B →	+0.584	+0.529	.003	.005	3	6
BRCA	CENPL →	+0.736	+0.456	<.001	<.001	3	6
OV	ARHGEF39 →	+1.104	+0.570	<.001	.002	3	6
GBM	ZGRF1 →	+0.753	+0.301	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,817 associations by consensus.

HAUS6 vs POLE2 — OV

Explore this scatter interactively →