HAUS6

Across TCGA patient cohorts, HAUS6 mutation is significantly associated with the RNA expression of many other genes, with 2,955 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAUS6-associated genes across cancer lineages are KLRD1, MIR6870, and HMBOX1-IT1. Each is linked with HAUS6 in more than 2 cancer types. Because this analysis shows association rather than direction, both HAUS6-to-partner and partner-to-HAUS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLRD1 grouped by HAUS6-low versus HAUS6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS6→partner) and Y-score (partner→HAUS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KLRD1 →	+0.286	+1.822	<.001	.003	3	3
BLCA	MIR6870 →	+0.736	+2.589	.001	.009	3	2
LIHC	HMBOX1-IT1 →	+0.130	+4.607	<.001	.004	3	2
COAD	RNU6-1187P →	+0.231	+3.343	.001	.007	3	2
UCEC	ZNHIT3 →	+0.307	+1.658	.005	.001	3	2
UCEC	TAF9 →	+0.592	+2.369	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,955 associations by consensus.

KLRD1 by HAUS6 expression — UCEC

Explore this box plot interactively →