HAUS6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HAUS6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,224 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAUS6-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Regulation of mitotic metaphase/anaphase transition, and Regulation of chromosome segregation. Each is linked with HAUS6 in more than 16 cancer types. Because this analysis shows association rather than direction, both HAUS6-to-partner and partner-to-HAUS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome condensation grouped by HAUS6-low versus HAUS6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS6→partner) and Y-score (partner→HAUS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of chromosome condensation →+0.224+1.169<.001<.001317
UPPER_AERODIGESTIVE_TRACTRegulation of mitotic metaphase/anaphase transition →+0.116+0.929.005.008317
SOFT_TISSUERegulation of chromosome segregation →+0.127+0.934<.001<.001317
SOFT_TISSUECentrosome cycle →+0.102+1.007<.001<.001317
LUNG_SCLCCentriole-centriole cohesion →+0.090+0.593<.001<.001316
UPPER_AERODIGESTIVE_TRACTMicrotubule organizing center organization →+0.101+1.368<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,224 associations by consensus.

Positive regulation of chromosome condensation by HAUS6 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of chromosome condensation in HAUS6-low vs HAUS6-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration