HAUS6

Across TCGA cell cohorts, HAUS6 mutation is significantly associated with the drug of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HAUS6-associated genes across cancer lineages are WYE-125132, GSK1059615, and AST-1306. Each is linked with HAUS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAUS6-to-partner and partner-to-HAUS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WYE-125132 grouped by HAUS6-low versus HAUS6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS6→partner) and Y-score (partner→HAUS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	WYE-125132 →	+0.673	+2.652	.007	.045	3	1
LARGE_INTESTINE	GSK1059615 →	+0.568	+2.652	.016	.045	3	1
LARGE_INTESTINE	AST-1306 →	+0.619	+2.684	.004	.035	3	1
LARGE_INTESTINE	Sphingosine Kinase 1 Inhibitor II →	+0.252	+2.786	.026	.037	3	1
LARGE_INTESTINE	Cyclophosphamide →	+0.314	+2.649	.046	.046	2	1
LARGE_INTESTINE	BDOCA000347a →	+0.337	+2.649	.042	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

WYE-125132 by HAUS6 expression — LARGE_INTESTINE

Explore this box plot interactively →