HAUS5

Across TCGA pan-cancer cohorts, HAUS5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated HAUS5 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HAUS5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HAUS5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LUAD, and LSCC are the cancer types where HAUS5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.895	0.267	.003	24	view →
LUAD	DFS	Median	III,IV	0.981	0.538	.001	20	view →
LSCC	OS	Median	II,III,IV	0.866	0.590	.012	4	view →
GBM	OS	Median	All	0.470	0.281	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

HAUS5–HNSC (DFS)

Open the HNSC breakdown →