HAUS5

Across TCGA patient cohorts, HAUS5 mutation is significantly associated with the RNA expression of many other genes, with 3,293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAUS5-associated genes across cancer lineages are EBP, PGP, and TEDC1. Each is linked with HAUS5 in more than 2 cancer types. Because this analysis shows association rather than direction, both HAUS5-to-partner and partner-to-HAUS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EBP grouped by HAUS5-low versus HAUS5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS5→partner) and Y-score (partner→HAUS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EBP →	+0.613	+1.673	.002	.007	3	3
UCEC	PGP →	+0.509	+2.392	<.001	<.001	3	3
UCEC	TEDC1 →	+0.447	+1.684	.004	.007	3	3
BLCA	CDRT15P7 →	+0.045	+3.106	<.001	.009	3	2
SKCM	RN7SL785P →	+0.102	+3.362	<.001	.006	3	2
UCEC	FAM72C →	+0.275	+2.815	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,293 associations by consensus.

EBP by HAUS5 expression — UCEC

Explore this box plot interactively →