HAUS5

Across TCGA cell cohorts, HAUS5 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAUS5-associated genes across cancer lineages are TBX5, EPPIN, and GZMK. Each is linked with HAUS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAUS5-to-partner and partner-to-HAUS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBX5 grouped by HAUS5-low versus HAUS5-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS5→partner) and Y-score (partner→HAUS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TBX5 →	+0.734	+4.350	<.001	.005	3	1
BLOOD_Leukemia	EPPIN →	+0.009	+4.507	<.001	.001	3	1
BLOOD_Leukemia	GZMK →	+0.680	+4.037	<.001	.004	3	1
BLOOD_Leukemia	TRIM51 →	+0.036	+4.567	.006	.001	3	1
BLOOD_Leukemia	HHLA1 →	+0.009	+3.551	<.001	.009	3	1
BLOOD_Leukemia	TACR3 →	+0.030	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

TBX5 by HAUS5 expression — BLOOD_Lymphoma

Explore this box plot interactively →