HAUS2

Across TCGA pan-cancer cohorts, HAUS2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated HAUS2 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher HAUS2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HAUS2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

PDAC, LUAD, and LSCC are the cancer types where HAUS2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.723	0.889	.004	43	view →
LUAD	OS	Quartile	All	1.000	0.838	.010	18	view →
LSCC	OS	Median	All	0.888	0.682	.005	15	view →
UCEC	DFS	Median	All	0.760	0.933	.003	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

HAUS2–PDAC (OS)

Open the PDAC breakdown →