HASPIN

Across TCGA cell cohorts, HASPIN mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HASPIN-associated genes across cancer lineages are SNPH, ELOVL4, and BHMT2. Each is linked with HASPIN in more than 1 cancer types. Because this analysis shows association rather than direction, both HASPIN-to-partner and partner-to-HASPIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNPH grouped by HASPIN-low versus HASPIN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HASPIN→partner) and Y-score (partner→HASPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNPH →	+1.060	+3.215	<.001	.009	3	1
LARGE_INTESTINE	ELOVL4 →	+0.605	+3.302	.001	.008	3	1
LARGE_INTESTINE	BHMT2 →	+0.214	+3.240	.001	.007	3	1
LARGE_INTESTINE	CCDC54 →	+0.106	+3.000	.001	.003	3	1
LARGE_INTESTINE	CLEC4F →	+0.189	+3.237	.003	.001	3	1
LARGE_INTESTINE	CDH12 →	+0.509	+3.748	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

SNPH by HASPIN expression — LARGE_INTESTINE

Explore this box plot interactively →