HARS2

Across TCGA patient cohorts, HARS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,480 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HARS2-associated proteins across cancer lineages are KDM3B, GEMIN5, and RARS1. Each is linked with HARS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HARS2-to-partner and partner-to-HARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HARS2 versus KDM3B in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS2→partner) and Y-score (partner→HARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KDM3B →	+0.359	+0.266	<.001	<.001	3	6
LSCC	GEMIN5 →	+0.315	+0.397	<.001	<.001	3	6
CCRCC	RARS1 →	+0.194	+0.334	<.001	<.001	3	5
PDAC	WDR55_S14 →	+0.797	+0.275	.004	.002	2	6
OV	HNRNPA0 →	+0.410	+0.385	.001	.006	3	5
CCRCC	NPM1 →	+0.269	+0.321	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,480 associations by consensus.

HARS2 vs KDM3B — GBM

Explore this scatter interactively →