HARS2

Across TCGA patient cohorts, HARS2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,750 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HARS2-associated genes across cancer lineages are HSPA9, PMP22, and WDR55. Each is linked with HARS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HARS2-to-partner and partner-to-HARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HARS2 versus HSPA9 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS2→partner) and Y-score (partner→HARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HSPA9 →	+0.440	+0.340	<.001	<.001	3	6
OV	PMP22 →	-0.752	-0.306	<.001	<.001	3	5
CCRCC	WDR55 →	+0.464	+0.471	<.001	<.001	3	5
OV	NDUFA2 →	+0.575	+0.380	<.001	<.001	3	5
UCEC	P2RY14 →	-1.057	-0.234	<.001	.001	3	5
BRCA	GNG2 →	-0.657	-0.480	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,750 associations by consensus.

HARS2 vs HSPA9 — OV

Explore this scatter interactively →