HARS2

Across TCGA cell cohorts, HARS2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,144 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible HARS2-associated genes across cancer lineages are HDAC3, ANKHD1, and RBM22. Each is linked with HARS2 in more than 17 cancer types. Because this analysis shows association rather than direction, both HARS2-to-partner and partner-to-HARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HARS2 versus HDAC3 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS2→partner) and Y-score (partner→HARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	HDAC3 →	+0.944	+0.726	.001	.001	3	18
LUNG_NSCLC_LUSC	ANKHD1 →	+0.877	+0.664	.001	<.001	3	18
BLOOD_Myeloma	RBM22 →	+0.788	+1.008	<.001	<.001	3	17
BLOOD_Myeloma	IK →	+0.844	+1.237	<.001	<.001	3	17
OESOPHAGUS	WDR55 →	+0.930	+0.835	<.001	<.001	2	18
LUNG_NSCLC_LUSC	HARS1 →	+0.928	+0.784	.002	<.001	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,144 associations by consensus.

HARS2 vs HDAC3 — LUNG_NSCLC_LUSC

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