HARS2

Across TCGA cell cohorts, HARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,692 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HARS2-associated GO terms across cancer lineages are mRNA splice site recognition, Establishment of protein localization to organelle, and Establishment of RNA localization. Each is linked with HARS2 in more than 11 cancer types. Because this analysis shows association rather than direction, both HARS2-to-partner and partner-to-HARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by HARS2-low versus HARS2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS2→partner) and Y-score (partner→HARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	mRNA splice site recognition →	+0.117	+0.732	<.001	<.001	3	12
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.057	+0.892	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.099	+0.722	<.001	<.001	3	11
PANCREAS	Regulation of transcription initiation by RNA polymerase II →	+0.080	+0.630	<.001	<.001	3	11
LARGE_INTESTINE	CAAX-box protein maturation →	+0.108	+0.535	<.001	<.001	3	11
PANCREAS	Regulation of DNA-templated transcription initiation →	+0.070	+0.594	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,692 associations by consensus.

mRNA splice site recognition by HARS2 expression — BLOOD_Lymphoma

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