HARS1

Across TCGA patient cohorts, HARS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,621 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HARS1-associated proteins across cancer lineages are GEMIN5, NPM1, and DIAPH1. Each is linked with HARS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HARS1-to-partner and partner-to-HARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HARS1 versus GEMIN5 in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS1→partner) and Y-score (partner→HARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GEMIN5 →	+0.290	+0.547	<.001	<.001	3	7
PDAC	NPM1 →	+0.339	+0.204	<.001	.002	3	7
CCRCC	DIAPH1 →	+0.254	+0.222	<.001	<.001	3	6
GBM	PHAX →	+0.271	+0.194	<.001	<.001	3	6
OV	TCOF1_S233 →	+0.932	+0.440	.001	.002	3	5
OV	UIMC1 →	+0.380	+0.496	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,621 associations by consensus.

HARS1 vs GEMIN5 — OV

Explore this scatter interactively →