HARS1

Across TCGA cell cohorts, HARS1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,453 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible HARS1-associated genes across cancer lineages are NPM1, CDH1, and GEMIN5. Each is linked with HARS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HARS1-to-partner and partner-to-HARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HARS1 versus NPM1 in PANCREAS, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HARS1→partner) and Y-score (partner→HARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	NPM1 →	+0.811	+1.323	.001	<.001	3	9
BREAST	CDH1 →	-3.751	-1.226	<.001	<.001	3	9
PANCREAS	GEMIN5 →	+0.932	+1.553	<.001	<.001	3	8
SKIN	HSPA9 →	+0.719	+1.444	<.001	.002	3	7
SKIN	BNIP1 →	+0.595	+1.118	.003	.008	2	8
STOMACH	PRELID1 →	+1.333	+1.893	.002	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,453 associations by consensus.

HARS1 vs NPM1 — PANCREAS

Explore this scatter interactively →