HARBI1

Across TCGA patient cohorts, HARBI1 protein abundance is significantly associated with the go_rna of many other GO terms, with 8 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HARBI1-associated GO terms across cancer lineages are CD40 signaling pathway, Paracrine signaling, and Positive regulation of spindle assembly. Each is linked with HARBI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HARBI1-to-partner and partner-to-HARBI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD40 signaling pathway grouped by HARBI1-low versus HARBI1-high in BRCA.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HARBI1→partner) and Y-score (partner→HARBI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD40 signaling pathway →	+0.115	+0.474	.009	.009	3	1
BRCA	Paracrine signaling →	-0.175	-0.564	.004	.009	3	1
BRCA	Positive regulation of spindle assembly →	+0.077	+0.609	.009	.002	2	1
BRCA	Pyrimidine nucleoside triphosphate metabolic process →	+0.063	+0.633	.008	.006	2	1
BRCA	Positive regulation of protein monoubiquitination →	+0.096	+0.482	.001	.004	2	1
BRCA	Negative regulation of protein dephosphorylation →	+0.096	+0.633	.002	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CD40 signaling pathway by HARBI1 expression — BRCA

Explore this box plot interactively →