HARBI1

Across TCGA patient cohorts, HARBI1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HARBI1-associated genes across cancer lineages are ASNS, EGFR, and PCNA. Each is linked with HARBI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HARBI1-to-partner and partner-to-HARBI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by HARBI1-low versus HARBI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HARBI1→partner) and Y-score (partner→HARBI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.401	+2.321	.027	.035	3	2
UCEC	EGFR →	-0.167	-3.000	.037	.036	3	1
UCEC	PCNA →	+0.262	+2.321	.015	.035	3	1
UCEC	STAT3_pY705 →	-0.412	-2.321	.001	.035	3	1
UCEC	INPP4B →	-0.463	-3.446	.004	.005	2	1
UCEC	Rad50 →	-0.321	-3.459	.008	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ASNS by HARBI1 expression — UCEC

Explore this box plot interactively →