HAPLN1

Across TCGA patient cohorts, HAPLN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,699 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAPLN1-associated proteins across cancer lineages are FKBP9, PDCD4, and ARHGAP15_S43. Each is linked with HAPLN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HAPLN1-to-partner and partner-to-HAPLN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAPLN1 versus FKBP9 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN1→partner) and Y-score (partner→HAPLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FKBP9 →	+0.574	+1.309	<.001	<.001	3	5
OV	PDCD4 →	-0.700	-1.150	<.001	<.001	3	5
LSCC	ARHGAP15_S43 →	-0.809	-0.778	<.001	<.001	3	4
GBM	RASAL3 →	-0.436	-1.109	<.001	.003	3	4
LSCC	RASAL3_S988 →	-0.638	-0.858	<.001	<.001	3	4
LSCC	SKAP1 →	-0.590	-0.724	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,699 associations by consensus.

HAPLN1 vs FKBP9 — BRCA

Explore this scatter interactively →