HAPLN1

Across TCGA patient cohorts, HAPLN1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,129 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HAPLN1-associated genes across cancer lineages are RN7SKP295, GRP, and TCTN2. Each is linked with HAPLN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HAPLN1-to-partner and partner-to-HAPLN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAPLN1 versus RN7SKP295 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN1→partner) and Y-score (partner→HAPLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP295 →	+0.616	+0.500	<.001	<.001	3	4
LSCC	GRP →	+1.392	+0.978	<.001	.009	3	4
BRCA	TCTN2 →	+0.590	+0.790	.001	<.001	3	4
GBM	CNTN1 →	+1.918	+1.101	<.001	<.001	3	4
PDAC	R3HDML →	-0.311	-0.853	.001	.002	3	3
LUAD	COL12A1 →	+1.093	+0.580	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,129 associations by consensus.

HAPLN1 vs RN7SKP295 — UCEC

Explore this scatter interactively →