HAP1

Across TCGA patient cohorts, HAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAP1-associated proteins across cancer lineages are FRMD6_S544, RIPK3_S339, and TMF1_S344. Each is linked with HAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HAP1-to-partner and partner-to-HAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAP1 versus FRMD6_S544 in UCEC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAP1→partner) and Y-score (partner→HAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FRMD6_S544 →	+0.667	+0.567	<.001	<.001	3	4
HNSC	RIPK3_S339 →	-0.451	-1.041	.001	<.001	3	4
LUAD	TMF1_S344 →	-0.541	-0.341	<.001	.008	3	4
UCEC	MXRA7 →	+0.845	+0.688	<.001	.003	3	4
LSCC	SBSN →	+1.441	+1.755	<.001	<.001	3	3
CCRCC	SLIT3 →	+0.455	+0.060	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,635 associations by consensus.

HAP1 vs FRMD6_S544 — UCEC

Explore this scatter interactively →