HAMP

Across TCGA patient cohorts, HAMP RNA expression is significantly associated with the protein abundance of many other proteins, with 14,467 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HAMP-associated proteins across cancer lineages are MYO1F, NCKAP1L, and ARHGAP25. Each is linked with HAMP in more than 7 cancer types. Because this analysis shows association rather than direction, both HAMP-to-partner and partner-to-HAMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAMP versus MYO1F in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAMP→partner) and Y-score (partner→HAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.732	+1.720	<.001	<.001	3	8
GBM	NCKAP1L →	+0.697	+1.758	<.001	<.001	3	8
OV	ARHGAP25 →	+0.984	+0.932	.003	.002	3	8
UCEC	PLEKHO2 →	+0.435	+0.677	<.001	<.001	3	8
LSCC	PLEKHO2_T311 →	+0.534	+0.453	<.001	<.001	3	8
GBM	WAS →	+0.655	+1.519	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,467 associations by consensus.

HAMP vs MYO1F — GBM

Explore this scatter interactively →