HAL

Across TCGA patient cohorts, HAL protein abundance is significantly associated with the RNA expression of many other genes, with 1,959 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HAL-associated genes across cancer lineages are CDKL1, SIX4, and CD9. Each is linked with HAL in more than 1 cancer types. Because this analysis shows association rather than direction, both HAL-to-partner and partner-to-HAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAL versus CDKL1 in HNSC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAL→partner) and Y-score (partner→HAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDKL1 →	-0.666	-1.357	.009	.009	3	1
HNSC	SIX4 →	-0.867	-1.022	.001	.007	3	1
HNSC	CD9 →	-1.109	-1.095	.002	.003	3	1
HNSC	NCAPD2 →	-1.099	-1.092	.002	.004	3	1
HNSC	PON2 →	-1.325	-1.797	.003	.002	3	1
HNSC	ITGB8 →	-0.882	-1.137	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,959 associations by consensus.

HAL vs CDKL1 — HNSC

Explore this scatter interactively →