HADHA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HADHA protein abundance is significantly associated with the RNA expression of many other genes, with 11,880 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HADHA-associated genes across cancer lineages are HADHB, MMS22L, and E2F7. Each is linked with HADHA in more than 5 cancer types. Because this analysis shows association rather than direction, both HADHA-to-partner and partner-to-HADHA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HADHA versus HADHB in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HADHA→partner) and Y-score (partner→HADHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVHADHB →+0.472+0.295<.001<.00136
OVMMS22L →-0.448-0.468.006<.00135
OVE2F7 →-0.826-0.256<.001.00235
UCECIRAK3 →-0.774-0.225<.001.00835
BRCAMCM5 →-0.627-0.265.004.00734
BRCACDK2 →-0.466-0.289<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,880 associations by consensus.

HADHA vs HADHB — OV

Per-sample scatter of HADHA vs HADHB in OV (Pearson r = 0.55).

Explore this scatter interactively →

Exploration