HADHA

Across TCGA patient cohorts, HADHA mutation is significantly associated with the RNA expression of many other genes, with 2,664 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HADHA-associated genes across cancer lineages are RPL31P9, UBL5P1, and MIR4698. Each is linked with HADHA in more than 2 cancer types. Because this analysis shows association rather than direction, both HADHA-to-partner and partner-to-HADHA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL31P9 grouped by HADHA-low versus HADHA-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HADHA→partner) and Y-score (partner→HADHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL31P9 →	+0.188	+4.399	<.001	.006	3	3
BLCA	UBL5P1 →	+0.162	+4.859	<.001	.004	3	2
UCEC	MIR4698 →	+0.263	+2.224	<.001	.002	3	2
UCEC	MIR4482 →	+0.766	+2.093	<.001	.003	3	2
SKCM	OR7E97P →	+0.018	+4.900	<.001	.002	3	2
SKCM	LINC02639 →	+0.150	+3.043	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,664 associations by consensus.

RPL31P9 by HADHA expression — COAD

Explore this box plot interactively →