HADH

Across TCGA patient cohorts, HADH protein abundance is significantly associated with the RNA expression of many other genes, with 13,533 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HADH-associated genes across cancer lineages are FAM189A2, SLC16A9, and EPHX1. Each is linked with HADH in more than 4 cancer types. Because this analysis shows association rather than direction, both HADH-to-partner and partner-to-HADH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HADH versus FAM189A2 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HADH→partner) and Y-score (partner→HADH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM189A2 →	+1.479	+0.443	.001	.002	3	5
OV	SLC16A9 →	+1.249	+0.507	.001	<.001	3	5
BRCA	EPHX1 →	+0.743	+0.442	<.001	<.001	3	5
COAD	DSE →	-0.496	-0.452	<.001	<.001	3	4
OV	USP53 →	+1.031	+0.461	.005	.001	3	4
GBM	COL1A2 →	-1.257	-0.193	.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,533 associations by consensus.

HADH vs FAM189A2 — UCEC

Explore this scatter interactively →