HADH

Across TCGA cell cohorts, HADH RNA expression is significantly associated with the go_rna of many other GO terms, with 5,786 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HADH-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of G2/MI transition of meiotic cell cycle, and Dentinogenesis. Each is linked with HADH in more than 13 cancer types. Because this analysis shows association rather than direction, both HADH-to-partner and partner-to-HADH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by HADH-low versus HADH-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HADH→partner) and Y-score (partner→HADH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.195	+1.184	<.001	<.001	3	14
BONE	Regulation of G2/MI transition of meiotic cell cycle →	+0.177	+1.196	<.001	<.001	3	13
BONE	Dentinogenesis →	-1.919	-0.950	<.001	<.001	3	12
BONE	Nuclear DNA replication →	+0.153	+0.723	.004	.006	3	12
BONE	Cell adhesion mediated by integrin →	-0.192	-0.841	<.001	<.001	3	12
BONE	DNA replication-dependent chromatin assembly →	+0.125	+0.653	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,786 associations by consensus.

DNA strand elongation involved in DNA replication by HADH expression — SOFT_TISSUE

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