HACL1

Across TCGA patient cohorts, HACL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,455 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HACL1-associated proteins across cancer lineages are TOP2B, PSIP1, and KIAA1143. Each is linked with HACL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HACL1-to-partner and partner-to-HACL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HACL1 versus TOP2B in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HACL1→partner) and Y-score (partner→HACL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.461	+0.298	<.001	<.001	3	6
GBM	PSIP1 →	+0.441	+0.274	<.001	<.001	3	6
UCEC	KIAA1143 →	+0.356	+0.427	<.001	.001	3	6
LUAD	QRICH1 →	+0.201	+0.316	<.001	<.001	3	5
HNSC	TBC1D5 →	+0.216	+0.564	<.001	<.001	3	5
HNSC	RPRD2 →	+0.327	+0.465	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,455 associations by consensus.

HACL1 vs TOP2B — GBM

Explore this scatter interactively →