Across TCGA patient cohorts, HACD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,139 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HACD4-associated proteins across cancer lineages are UBA7, ESF1, and CLIC2. Each is linked with HACD4 in more than 6 cancer types. Because this analysis shows association rather than direction, both HACD4-to-partner and partner-to-HACD4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD4→partner) and Y-score (partner→HACD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBA7 →	+0.396	+0.719	<.001	.001	3	7
UCEC	ESF1 →	-0.423	-0.429	<.001	.003	3	7
HNSC	CLIC2 →	+0.494	+0.710	<.001	<.001	3	7
COAD	NFATC2 →	+0.671	+0.457	.001	.003	3	6
HNSC	PSMB6 →	-0.423	-0.777	<.001	<.001	3	6
LSCC	RCOR1_S260 →	-0.457	-0.544	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,139 associations by consensus.

Exploration

HACD4 survival (RNA) · tumor vs normal (RNA) · all HACD4 data types