Across TCGA cell cohorts, HACD4 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HACD4-associated genes across cancer lineages are MFSD2A, OR10W1, and ZNF771. Each is linked with HACD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HACD4-to-partner and partner-to-HACD4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD4→partner) and Y-score (partner→HACD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MFSD2A →	+1.392	+3.067	.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.008	+2.977	<.001	.006	3	1
LARGE_INTESTINE	ZNF771 →	+0.721	+3.064	<.001	.009	3	1
LARGE_INTESTINE	OR52H1 →	+0.020	+2.669	<.001	.004	3	1
LARGE_INTESTINE	BAAT →	+0.371	+3.273	.001	.006	2	1
LARGE_INTESTINE	MRRF →	+0.475	+3.215	.003	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

HACD4 survival (RNA) · tumor vs normal (RNA) · all HACD4 data types