HABP4

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, HABP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HABP4 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher HABP4 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated HABP4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, LSCC, and HNSC are the cancer types where HABP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.9420.726<.00140view →
LSCCDFSMedianII,III,IV0.6330.892.00620view →
HNSCOSQuartileIII,IV0.9530.784.0058view →
LUADDFSMedianAll0.7270.497.0136view →
PDACOSTertileIV0.9160.231.0243view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HABP4–CCRCC (OS)

Kaplan–Meier survival curve for HABP4 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration